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Non-Profit, Retail, Travel and Lodging

Many of the online directories focus towards one market segment or audience profile. Here, we target the "best in class" for each of the served markets by industry leaders in their respective fields. Find a category that you feel is most relevant to the content of your site, or that attracts a customer demographic you wish to reach. Provide a title and URL and submit to this directory.

Corporate Business

Business web directory and online Internet marketing center, offering powerful promotion opportunities to your business and website. Maximize traffic to your website by submitting to the directory. Categorized in 7 main groups, including Consulting, Manufacturing, Internet Services, Professionals, Health, Pharmaceutical, Software & Telecommunications and Transportation.

Associations, Foundations & Non-Profit


Retail & Ecommerce

Retail Directory businesses and Retail Directory companies. View the B2B Directory Guide business directory and find a complete listing of companies by restaurants, travel and lodging, clothing, publishing, sports and health, and gifts and arts.

Clothing & Accessories

Coloriffics is a national manufacturer and retailer of Special Occasion Shoes, Evening Shoes, Dyeable Shoes

Category: Special Occasion Shoes, Evening Shoes, Dyeable Shoes

Sizzle, a division of Coloriffics, focuses on tween and teen Evening Prom Shoes, Silver Prom Shoes, Prom Shoes

Category: Evening Prom Shoes, Silver Prom Shoes, Prom Shoes

Offers a range of products and services for markets including Wedding Shoes, Wedding Sandals, Bridal Shoes. Coloriffics Shoes- Speen and Co. has been a member since 2009 in the Clothing and Accessories directory.

Category: Wedding Shoes, Wedding Sandals, Bridal Shoes

Provides full-service adult diaper, plasticpants, products for incontinence services for customers needing needing incontinence protection for day-to-day living and comfort. Visit to take advantage of our special rates today.

Category: Adult Diaper, Plasticpants, Products For Incontinence

Retailer of rubberpants, plastic wear, adult baby. Located in the Clothing and Accessories directory since 2011, Fetware strives to provide superior service and sell the highest quality products.

Category: Rubberpants, Plastic Wear, Adult Baby

Gifts, Arts & Other

Find out where you can get MA persian Rug Cleaning, NH oriental rugs, persian and oriental rugs, persian carpets, NH oriental rug cleaning. Since 2010, Persian Rugs of Nashua, NH has been listed in the Gifts Arts and Other directory.

Category: Ma Persian Rug Cleaning, Nh Oriental Rugs, Persian And Oriental Rugs, Persian Carpets, Nh Oriental Rug Cleaning

Music, Gaming and Other

Burkart Flutes is a premiere flute and piccollo company. Their custom flutes are designed by award-winning artists for bringing out the best in classical, jazz and other styles with flair.

Category: Professional Flute, Custom Piccolo, Flute And Piccolo Headjoint

Providing high quality new Burkart-Phelan-Resona resona flutes. Since 2012, Burkart-Phelan-Resona has participated in the Retail directory.

Category: Resona Flutes



Category: Publishing

Sports and Health


Hotels & Restaurants


Consumer Transportation



business directory | corporate, financial & education directory | real estate & search engine directory | manufacturing directory | software, non-profit & retailers directory | company directory

First SPF Research Grants are awarded! Press Release

The Spastic Paraplegia Foundation is dedicated to advancing research and ultimately finding the cures for two groups of closely related upper motor neuron disorders termed Hereditary Spastic Paraplegia and Primary Lateral Sclerosis. The conditions share the common pathologic feature of degeneration principally of the upper motor neurons. 

The impetus for forming the Foundation was inspired by the accelerating pace of research. Many HSP genes have been discovered as well as a gene for PLS. Animal models for these disorders are underway. These will enable investigators to uncover the biochemical processes that cause nerve degeneration and identify therapy targets. Gene discovery continues to move forward as well as research to understand the proteins created by known genes.

Additionally, researchers feel that compounds showing compelling data for treatment for the motor neuron disease amyotrophic lateral sclerosis (ALS) may be promising for upper motor neuron conditions as well. These include Rilutek (the only FDA approved treatment for ALS), Celebrex, Creatine, Minocycline and antioxidants Vitamin E, alpha lipoic acid and CoQ10. Please visit Publications to review recent HSP and PLS research and Research at the ALS Association to stay current on ALS research.

An increased focus on our diseases is timely and critical. Investigators claim there is overlap, commonality and convergence along the continuum of motor neuron diseases as well as other neurologic conditions such as spinal cord injury and Alzheimer's Disease. Common threads link neurological conditions affecting millions of Americans. 

While much research has been underway on the motor neuron disorder ALS and other neurologic conditions, there has been little attention on the category of upper motor neuron disorders until now. SPF supports research specifically on upper motor neuron conditions.

Fostering communication and collaboration between researchers, improving their access to data and providing direction to their efforts will accelerate the pace towards finding the cures. We are hopeful that findings in SPF disorders will not only help us, but also lead to breakthroughs for other conditions.

The SPF will seek to support new initiatives, take smart risks and make sure research dollars are spent wisely on pertinent PLS and HSP research. The Spastic Paraplegia Foundation is a volunteer driven, publicly supported organization. Make a contribution to research or discuss ways your company can become a partner.

PLS and HSP genes discovered thus far:

PLS genes:

HSP genes:

Article by John K. Fink, M.D.: The Hereditary Spastic Paraplegias - Nine Genes and Counting

(two more genes have been discovered since that article was published)

Recommended Links:


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