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RepelaCOAT™
Anti-microbial Coating
RepelaCOAT™coatings are
Effective:
RepelaCOAT™ prevents growth of commonly occurring organisms such as E. Coli, staph, and candida.
Safe:
RepelaCOAT™ maintains a slow release profile that minimizes toxicity to surrounding tissue.
Long Lasting:
RepelaCOAT™ has demonstrated effectiveness for up to 30 days.
Aqueous:
RepelaCOAT™ coatings, since they are based on the BioLAST platform, contain no organic solvents. Safer and cleaner manufacturing processes are used and any concerns about residual solvents in a device are eliminated.
Durable:
RepelaCOAT retains it's physical integrity even after hundreds of cycles.
Lubricious:
RepelaCOAT™ incorporates lubricious polymers that reduce patient trauma and increase ease of handling.
How does RepelaCOAT™ work?
RepelaCOAT™ is part of the BioLAST technology platform. BioLAST's supporting polymer network is crosslinked and covalently bound to the substrate. This network is normally non-swellable in water. In this patent pending coating, silver salts and/or antibiotics are ionically bonded to the supporting polymer. In the presence of the sodium or calcium ions characteristic of body fluids, the anti-microbial agents ion exchange with these physiological cations. Long chain hydrophilic polymers incorporated in the coating adsorb water molecules and facilitate the ion exchange. Rather than exhibiting a huge "spike" of activity that diminishes rapidly over time and that may be toxic to the surrounding tissues RepelaCOAT™ prevents bacterial adherence by it's slow ion-exchange release of anti-microbial agents.

Anti-microbial Coating
Developed on BioLAST platform, RepelaCOAT™ is an infection-resistant medical device coating with a patent pending, ion-exchange release mechanism. Unlike most antimicrobial coatings that have only a brief, initial spike of activity, RepelaCOAT™ can be customized to have a controlled, initial "peak release" followed by a sustained release of anti-microbial agents in the presence of blood or urine.
Antimicrobial Profile - Silver Salt

Antimicrobial Profile - Antibiotic

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